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NAIL FUNGUS: TREATMENT METHODS

TOP 5 TOPICAL NAIL FUNGUS TREATMENTS (2017):

Below are the top rated over-the-counter topical nail fungus treatments on market – each has been thoroughly evaluated by our editors, health professionals, and fellow Nail Fungus sufferers. All of the following treatments are topical solutions to Nail Fungus. The chart at the bottom of this page explains the advantages of Topical medication over Oral and Surgical options.



EmoniNail™
Rank 1 - EmoniNail

Funginix
Rank 2 - Funginix

Zetaclear
Rank 3 Zetaclear

Naturasil
Rank 4 - Dermisil

Nail Rx
Rank 5 Nail RX
1. Treatment Rating99.5 / 10089.7 / 10086.5 / 10080.1 / 10078.4 / 100
2. Customer Rating4 Star Nail Fungus Product3.5 Star Nail Fungus Product3 Star Nail Fungus Product3 Star Nail Fungus Product
3. Editor Review
4. MSRP$59.95
Visit Official Site
$59.95$49.95$35.95$49.95
5. Patients Treated (est.)20,000+20,000+20,000+10,000 - 20,00010,000 - 20,000
6. Success Rate*89.4%83.2%76.1%71.1%68%
7. Treatment TimeShortest (1-2 Months)Average (2-4 Months)Average (2-4 Months)Average (2-4 Months)Long (3-6 Months)
8. Product Safety Safe to UseSafe to UseSafe to UseSafe to UseSafe to Use
9. Return PolicyRisk FreeRestock FeeRisk FreeRisk FreeUnknown
10. Customer Support5 Star Nail Fungus Product3 Star Nail Fungus Product4 Star Nail Fungus Product4 Star Nail Fungus Product4 Star Nail Fungus Product

If your nails are infected with Nail Fungus there are two actions you must now take: (1) Find treatment and (2) understand how to use that treatment. Our Treatment Guide provides step-by-step instructions for achieving maximum effectiveness with topical treatments.

Review of Our Top Pick Topical (OTC) Nail Fungus Treatment

EmoniNail RANK: #1

Review Summary

EmoniNail is our top-most recommended product for the topical treatment of fingernail and toenail fungus. The superior blend of proven ingredients make EmoniNail an effective* formula to dramatically improve the vitality and appearance of the nail bed and surrounding skin. The formulation, which was last updated in 2016 combines a powerful anti-fungal active ingredient with nail penetrating essential oils which can result* in superior effectiveness in the treatment of nail fungus. This conclusion of superiority is supported by our customer reviews and an overall success rate higher than any other product on the market.

Our experts agree that the EmoniNail treatment formulation is the ideal combination.

Users consistently observe a reduction of redness, pain, and irritation within weeks*. Within months the average users sees complete removal of visible nail fungus. The vast majority (95%+) of users experience regrowth of clear, revitalized, fungal-free nails*. We recommend EmoniNail in conjunction with diligent adherence to our treatment guide for maximum effectiveness.

Active Ingredient: Undecylenic Acid, 10%

Means of Nail Penetration: Tea Tree Oil

*Based on aggregated user reviews. Not a scientific study of product efficacy. Individual results may vary.

Top 30 Topical (OTC) Nail Fungus Products (2017)

Top 30 Topical (OTC) Nail Fungus Products (2024)

RankProductTreatment RatingEditor ReviewPatients Treated (est.)Success Rate*Rank ChangeMSRP
1EmoniNail
Rank 1 - EmoniNail
99.5 / 10020,000+89.2%+1$59.95
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2Funginix (Fungisil)
Rank 2 - Funginix
89.7 / 10020,000+83.2%-1$59.95
3Zetaclear
Rank 2 Zetaclear
86.5 / 10020,000+76.1%+1$49.95
4Dermisil
Rank 4 - Dermisil
80.1 / 10010,000 - 20,00071.1%-1$29.95
5Nail Rx
Rank 5 Nail RX
78.4 / 10010,000 - 20,00068%0$39.95
6Pedifix Fungasoap71.1 / 10010,000 - 20,00067%-3$49.95
7Opi Fungus Fix69.6 / 10010,000 - 20,00066%0$44.95
8Omega Labs Fungus Treatment68.1 / 10010,000 - 20,00065%0$34.95
9Fungi Nail Brand67.9 / 10010,000 - 20,00056.4%0$25.95
10Excilor65.7 / 10010,000 - 20,00052%0$21.95
11Dr G.63.4 / 1005,000 - 10,00049%0$29.95
12Claripro60.9 / 1005,000 - 10,00047%0$29.95
13Blue Goo59.8 / 1005,000 - 10,00047%+1$9.95
14Amoresse Thymol57.4 / 1005,000 - 10,00044%0$29.95
15Good N Natural Nail Fungus56.1 / 1005,000 - 10,00043%+2$15.99
16Keractil55.4 / 1005,000 - 10,00039%0$19.95
17Mycocide54.3 / 1005,000 - 10,00038%0$9.95
18Pedi-Cure50.8 / 1001,000 - 5,00038%0n/a
19Barielle Fungus RX49.7 / 1001,000 - 5,00037%+1$15.95
20OPI Fungus Fix (2003 Formula)49.1 / 1001,000 - 5,00036%0$19.95
21FungaSoap (Original Formula)48.9 / 1001,000 - 5,00035%0$8.14
22Saprox48.2 / 1001,000 - 5,00035%0$42.90
23Deggurcide47.2 / 1001,000 - 5,00034%0$39.95
24Anidulafungin (Eraxis)46.3 / 1001,000 - 5,00033%0$49.95
25Nail Tek45.1 / 1001,000 - 5,00032%0$8.40
26PurNail43.5 / 100< 1,00031.2%-5$54.95
27Lamisil Terbinafine42.1 / 100< 1,00030.9%0$12.95
28Varisi41.3 / 100< 1,00029.9%0$9.95
29Tineacide40.4 / 100< 1,00033.3%0$15.36
30Tammy Taylor Thymolize39.6 / 100< 1,00032%+1$13.23
31Radiant Health38.5 / 100< 1,00032%-1$19.95
*Based on aggregated reviews. Not a scientific study of success rate

Topical Prescription Drugs which are used to Fight Fungal Infections of the Nails

Topical prescription remedies may be used alone or with oral agents. One benefit of using topical remedies is that the medication may be applied directly to infected areas. The risk of systemic complications due to side effects is reduced. Theoretically, more medicine should get directly to the area which needs treatment.
A down side of using topical preparations is that more time may be needed for administration when compared with the amount of time required to take oral drugs. Unless topical remedies are well formulated, many of the healing properties may not be available, as absorption into the nails and surrounding tissues may be poor. Topical remedies are more likely to cause localized irritation than oral remedies do. It may be more difficult to use a topical remedy on your toenails if you have mobility issues. The cost of prescription treatments may be prohibitive.

The following charts compare the benefits and shortcomings of currently available FDA approved oral medications which are used to treat fungal infections of the nails.

Generic NameBrand NamesAverage Monthly CostHow UsedBenefitsPrecautions and Potential Side Effects
Tavaborole
Kerydin
$1265.00 for a 10mL. BottleApplied directly to the toenails daily for 48 weeks.Serious negative reactions are rare.Seek medical assistance if you experience: swelling of the face or throat, difficulty breathing, or hives.

Irritation, redness, itching, swelling, or peeling of the tissues surrounding the treated nail may occur. Ingrown toenails may develop.

Promptly wipe the medication off of your skin if it gets on it. Do not apply medication to any tissues except affected nails.

The medication is flammable.
Efinaconazole
Jublia
$468.00 for 4 mLApply to the infected nail and surrounding skin daily for 48 weeks.Serious negative reactions to the medication are rare.Seek medical assistance if you experience: swelling of the face or throat, difficulty breathing, hives, irritation or pain at the application site, blisters, or if you develop an ingrown toenail.

It is unknown if this medication passes into breast milk. Avoid use during pregnancy or while breastfeeding.

The medication is flammable.
Ciclopirox
Penlac
$930.00 for Penlac brand 6.6 mL

$30.00 for generic, 6.6mL
Apply this nail lacquer directly to the nails every day. Do not wash the area for at least 8 hours. Use alcohol to remove the medication from your nails.
The medication may need to be used for 48 weeks to be fully effective.
Serious negative reactions to the medication are rare.
Reduces the rate of reinfection by 70%
Seek medical assistance if you experience: swelling of the face or throat, difficulty breathing, hives, irritation or pain at the application site, blisters, or if you develop an ingrown toenail.

It is unknown if this medication passes into breast milk. Avoid use while breastfeeding.
The medication is flammable.

Cure rate to get rid of infection is only 7%

Notify your doctor of all medications which you take. Be sure that he or she knows your complete health history. This is especially important if you have been diagnosed with a seizure disorder, diabetes or an immune problem.

Oral Prescription Medications which are Used to Treat Fungal Infections of the Nails

If you choose to take an oral medication to treat your nail fungus; there are several agents for your health care provider and you to choose from. The success rates of oral medications which are used to treat nail infections are approximately fifty percent. Even if the infection is deemed “cured”, it usually recurs in between two and five out of ten people. (Del Rosso, 2014) Oral medications are generally easier to use than topical remedies. They are more likely to cause detrimental side effects than topical agents.

Almost all of the oral agents possess potential side effects which can only be described as very dangerous and potentially life threatening. If you choose to use an oral agent, be sure that you and your doctor discuss your health history and current medications in detail.​

It is essential that you weigh the risks of treatment carefully with the potential benefits. While nail fungus is not life threatening, nor does it cause serious illness; the drugs which are used to treat the condition may cause serious illnesses or in rare cases, deafness or death. If you have underlying health issues, are pregnant, want to become pregnant or are breastfeeding it is critically important that you learn everything you can about the treatment before starting an oral medication as the drugs may cause harm to your baby.

The following charts compare the benefits and shortcomings of currently available FDA approved oral medications which are used to treat fungal infections of the nails.

Generic NameBrand NamesAverage Monthly CostHow UsedBenefitsPrecautions and Potential Side Effects
GriseofulvinFulvicin, Gifulvin, Gris-Peg Brand name $240.00/ 30 500mg.tablet

Generic $180.00/ 30 500mg. tablets
Take the medication by mouth on a daily basis. It must be taken for up to one year to resolve infections of the nails. Treats discoloration of nails.Not recommended for use if liver disease, lupus, or porphyria is present.

Does not work well for fungal infections of the nails.

Seek medical assistance if you experience: swelling of the face or throat, difficulty breathing, hives, numbness or tingling of the extremities, changes in mood, confusion, sunburn-like rash, hearing changes, butterfly-shaped facial rash, joint or muscle pain. Notify your doctor if these side effects occur: yellowing of the skin or eyes, abdominal pain, persistent nausea or vomiting, changes in urination, fever, or sore throat.

Prolonged use of this medication may encourage the development yeast infections of the mouth and vagina.

Do not use if you are pregnant, may become pregnant, or are nursing. May damage an unborn baby. Males should avoid impregnating a female. It is unknown if the medication continues to affect sperm after use is discontinued.

Avoid alcohol and limit sun exposure.

A complete blood count, liver, and kidney function tests must be performed periodically during treatment.
Terbinafine Lamisil Lamisil brand (30) 250 mg. tablets $700.00

Generic (30) 250 mg. tablets $6.00
Dosing regimen variesFew side effects. 35-50% cure rate for fungal infections of the nails.

Inexpensive if generic drug is used.
May cause gastrointestinal distress and be harmful for individuals who have liver disease. Abnormalities of the liver enzymes, drug-induced hepatitis and drug interactions are less frequent compared to itraconazole. (Leelavathi, 2014)

Changes in the sense of taste may occur. Limit alcohol consumption and sun exposure while taking.

Use during pregnancy and while breastfeeding is not recommended.

Seek medical help if the following occur: fever, sore throat, swollen glands, mouth sores, blood in urine, dark colored urine, chest pain, irregular heartbeat, hives, shortness of breath, severe abdominal pain, nausea or vomiting which does not go away, yellowing of the eyes or skin, or loss of appetite.
IitraconazoleSporanoxBrand name: (60) 100 mg. capsules $1380.00

Generic (60) 100 mg. capsules $380.00
Dosing schedules may vary. Usually taken twice daily. Sometimes used for pulse, intermittent, dosing. Take the medication on a full stomach. Do not take at the same time as antacids.

Take with a cola beverage if you use medications which reduce stomach acid or if you suffer from achlorhydria.
25-40% cure rate for fungal infections of the nails.Low cure rate, especially for toenail infections. Not approved by the FDA as a treatment for fungal infections of the toenails.

May interact with many other medications; especially antibiotics and medications used to treat asthma. Make sure your doctor has a complete list of medications which you are taking before starting to use this medication. The drug may cause life threatening cardiac problems if combined with certain types of medications. Do not use this medication if you have specific types of heart problems, including congestive heart failure, as life threatening reactions may occur.

May promote liver problems including hepatitis. Use caution if underlying liver disease is present. Monitor liver function tests during treatment. Notify your doctor if you experience severe abdominal pain, nausea or vomiting which does not go away, yellowing of the eyes or skin, or loss of appetite as rare, and possibly fatal reactions may occur.
Do not use if you have kidney disease. Use with caution if you have COPD. Be sure that your doctor is aware of your complete medical history if using this medication because it has harmful effects when certain illnesses are present.

Seek medical assistance if you experience: swelling of the face or throat, difficulty breathing or hives, swelling of the legs or feet, sudden tiredness, or weight gain.

May cause dizziness or drowsiness.

Older adults have an increased risk of hearing loss if this drug is used. Hearing loss may be temporary or permanent. Ringing in the ears may occur when this medication is employed.

Do not use if you plan to become pregnant, are pregnant, or are breastfeeding. Take measures to prevent conception for at least two months after discontinuing the use of this medication.

Notify your healthcare provider if you experience: a fever, persistent sore throat, changes in urination or sexual activity, hair loss, a fast or irregular heartbeat, depression, or enlarged breasts if you are male.
FluconazoleDiflucan(30) 150 mg generic tablets $8.00. Due to variable dosing regimens, cost may be more.Dosing schedules are variable.InexpensiveNot as effective as other antifungal agents used to treat nail infections.

May interact with other medications including, but not limited to, those used to treat seizure disorders and diabetes. The medicine may increase the risk of bleeding if used in conjunction with blood thinners. May interact with antibiotics.

Seek medical assistance if you experience: swelling of the face or throat, difficulty breathing or hives.

May cause dizziness, headache, rash changes in taste and digestive upsets.

Caution must be used if liver or kidney problems are present. May cause liver damage. White blood count cell and platelet levels may decrease when used.

Adverse reactions are more likely to occur if HIV infection is present.

A rash may occur. Notify your doctor if it does.

EmoniNail

RANK: #1


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GG Healthworks, Inc. EmoniNail SKU UPC Model

Amazing results

Jun 19, 2016 by Melane Strokes

Results!! This nail fungus cream actuallly works. The top right of the nail was completely yellow and black before i started using this. After only about a week it started lighten. And i got optimistic. And then no real progress for about a month, and then i finally saw the nail starting to grow out and thank goodness the new nail growing in was completely clear!

IT WORKED! WOOO. Kept using for another few weeks and then stopped and now i’m 100% fungus free.

I still have plenty of cream left after ordering 3 bottles.


Wasn’t sure at first. But working

Jun 08, 2016 by Cody Kenney

I have been at this treatment for over a month. My nails started to improve until I put shoes on. As soon as I did the keritan was once again visable. I have found that I am going through alot of this product. So if you don’t have to wear shoes for any reason this product works very well.


Same Active Ingredient, better amount

Nov 27, 2015 by Ray Wein

There’s another product (not listed) that has the same active ingredient at a 25% proportion, and it causes extreme amount of skin damage when used every day. This product has 10% which seems to allow me to keep applying again and again without any irritation. Great formula. Great results.


success at last…

Jan 19, 2014 by Lisa S.

Started applying Emoni nail twice a day as instructed. I also filed down my infected nails as they instructed. After a couple weeks the redness around my nails has disappeared but the nails were unchanged. I contacted emoni nial support and they said to “keep at it”. They were very responsive. After about a month of applying the stuff I noticed my nails started to turn white-ish. Almost as if they were being stained by the treatment. It took another few weeks before I saw, to my delight, some normal nail growing in at the base of my big toenail. I contacted support again and they told me to keep applying until I was certain that the nail was now growing in clear and toenail fungus free. I kept applying for another week or so and sure enough the new nail growing in was PERFECT. Just like my pre-nail fungus days. I stopped the treatment and just kept cutting off the old infected nail as it grew out and eventually it was totally gone. I am now nail fungus free and wanted to help others out there by sharing my story.

Response: Disclaimer: Individual results may vary.


Success!

Dec 28, 2013 by Squidlet

I purchased EmoniNail based on this site’s #1 ranking recommendation.
A few weeks into treatment my nails are much better. The infection is growing out and the new nail looks good.
I would say in another few weeks-month my nails will be back to normal – so it really did work within months.
THANK YOU!

Response: Disclaimer: Individual results may vary.


Works great.

May 02, 2013 by Otis R. Rarick

Purchased 3 bottles of funginix for my 89 year old father. He is on a bunch of meds so we didn’t feel comfortable putting him on another oral Rx.

Luckily EMONI NAIL worked perfectly. Few months and fantastic improvement. He actually says he “likes” this product. Could not ask for more.

Response: Disclaimer: Individual results may vary.


Seems to work!

May 01, 2013 by Yang Lee

I am only a few weeks into treatment but I must say I am feeling awfully optimistic. Already seeing results. 4-stars for now, if a few months I’ll update if the black nails are totally healed.

Response: Disclaimer: Individual results may vary.


Finally!

Apr 22, 2013 by Tess Roman

What a rollercoaster ride. After oral meds failed I was soo ready to go under the knife. Out of fear of surgery my husband recommended I look around on google rather than just trusting every word my doctor says.

Well, I found this site, found EmoniNail, and now, a few months after starting treatment, I can confidently say that I am nail fungus free (or at least very close).

Thanks!

Response: Disclaimer: Individual results may vary.


Cured my ugly nail. Finally.

Apr 12, 2013 by Manny Trenton

I had yellow thick nails from the time I turned 40 until this last year (I’m 67 now). I tried just about everything out there when I first started seeing my nails get weird. Nothing worked. I gave up.

Then about 6 months ago I saw a TV ad for Emoninail and decided to give it a shot. Guess what? It worked. I guess the technology has advanced enough. Next thing I know they will have an app to cure nail fungus. Just kidding.

Response: Disclaimer: Individual results may vary.


Amazing product with a good price

Mar 01, 2013 by Bonnie Lammel

This treatment was a good price and really worked incredibly well. Very impressive performance. Everytime you finish showering apply this to all infected nails. Within a few weeks all the redness goes away, then in a few more months the nail started to clear – almost completely. I recommend emoni nail to anyone else who suffered like I did for 10+ years of nail fungus.

Response: Disclaimer: Individual results may vary.


4.9 5.0 13 13 Results!! This nail fungus cream actuallly works. The top right of the nail was completely yellow and black before i started using this. After only about a week it started lighten EmoniNail
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Global Nail Fungus Executive Team:

Sandy Getzky - Executive Coordinator

Sandy is an experienced manager of medical research operations and authority content creation.

Pat B. - Head of Research

Pat holds a PhD in Natural Health and has been a Registered Nurse for 35 years.

Diana Arevalo - Contributor and Research Coordinator

Diana is a registered Nutritionist-Dietitian. Graduated with a degree in Nutrition and Dietetics.

Gary Smith - Medical Presenter

Gary is a professional medical presenter with over 35 years in this industry.

Tell Your Story

Help the community by sharing your experience with nail fungus.

Nail Fungus Treatment Survey

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Tell Your Story

Help the community by sharing your experience with nail fungus.

Nail Fungus Treatment Survey

(View Survey Results)
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Physician Login:
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Global Nail Fungus Executive Team:

Sandy Getzky - Executive Coordinator

Sandy is an experienced manager of medical research operations and authority content creation.

Pat B. - Head of Research

Pat holds a PhD in Natural Health and has been a Registered Nurse for 35 years.

Diana Arevalo - Contributor and Research Coordinator

Diana is a registered Nutritionist-Dietitian. Graduated with a degree in Nutrition and Dietetics.

Gary Smith - Medical Presenter

Gary is a professional medical presenter with over 35 years in this industry.

Tell Your Story

Help the community by sharing your experience with nail fungus.

Nail Fungus Treatment Survey

(View Survey Results)
Physician Login:
Click here

Compare Treatments

Tell Your Story

Help the community by sharing your experience with nail fungus.

Nail Fungus Treatment Survey

(View Survey Results)
Donate:
Your donation is needed to support medical research on nail fungus. Click here

Physician Login:
Click here

Like Us On Facebook

Reviewed and writing contributions by
Dr. Jacob Moss, M.D. General Practitioner, Colorado

MD Information

  • MD and JD from Southern Illinois University schools of Medicine and Law
  • Honors: Surgery Clerkship, Internal Medicine Clerkship, Neurology Clerkship, Urology Sub-Internship
  • Published in over 10 Peer Reviewed Medical Journals
Complete Guide to Removing Nail Fungus
Complete Guide to Removing
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Our Mission

The Global Nail Fungus Organization was founded with one goal: Fight Nail Fungus. We work towards this goal by providing resources, education, and solutions to the 35 million people currently suffering from finger and toenail fungus in America and the millions more around the world.