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Which Treatment Is Actually the Most Effective? We Reviewed 28 Of the Most Popular Nail Fungus Treatments Claiming to Be the Best 

Which Brand of Product Treatments Are Actually the Most Effective?

Best Way to Kill
Toenail Fungus is 
at the Source w/
a Combination of
Undecylinic Acid
& Essential Oils.
-GNFO Editor

Nail fungus can be an embarrassing condition, but it’s a lot more common than you think. There’s absolutely no shame in acknowledging it and treating it. In fact, it’s better to address the infection during its early stages than when it begins spreading, because then it can be a lot more difficult to get rid of.

Nail fungus usually starts out as a discolored spot under the tip of your fingernail or toenail, typically in a yellow, brown, or white color. Milder conditions usually go unnoticed and don’t require treatment, but if it spreads or gets worse, the fungal infection can cause your nail to thicken, break or loosen, which can be very painful.

Don’t panic, though. We’re here for you! We’ll tell you everything you need to know about nail fungus and how to get rid of it. Additionally, to save you time and money, we’ve added some quick tips on what to look for in an effective topical nail fungus treatment.

WHY A TOPICAL TREATMENT IS ESSENTIAL TO ELIMINATING NAIL FUNGUS

You might have tried a few home remedies out already, without too much success in treating the infection. Nail fungus needs a concentrated effort to be completely eradicated. Even after a successful treatment, it could come back, so having a topical treatment around would not be a bad idea.

The most effective topical treatments make use of all-natural ingredients in combination with a known fungus-destroying agent. These treatments should be easily absorbed by the nail and surrounding skin to kill the nail fungus and promote healthy nail regrowth.

We Reviewed 28 Of the Most Popular Nail Fungus Treatments On the Market Today

Nail fungus can be an embarrassing condition, but it’s a lot more common than you think. There’s absolutely no shame in acknowledging it and treating it. In fact, it’s better to address the infection during its early stages than when it begins spreading, because then it can be a lot more difficult to get rid of.

Nail fungus usually starts out as a discolored spot under the tip of your fingernail or toenail, typically in a yellow, brown, or white color. Milder conditions usually go unnoticed and don’t require treatment, but if it spreads or gets worse, the fungal infection can cause your nail to thicken, break or loosen, which can be very painful.

Don’t panic, though. We’re here for you! We’ll tell you everything you need to know about nail fungus and how to get rid of it. Additionally, to save you time and money, we’ve added some quick tips on what to look for in an effective topical nail fungus treatment.

KILL BACTERIA DEEP UNDERNEATH NAILS & PREVENT FUTURE GROWTH OF FUNGUS

The most effective topical treatments make use of all-natural ingredients in combination with a known fungus-destroying agent. These treatments should be easily absorbed by the nail and surrounding skin to kill the nail fungus and promote healthy nail regrowth.

NNFO-Microscopic-Nail

3 MYTHS ABOUT NAIL FUNGAL INFECTIONS

There are tons of success stories about treating nail fungus, but with them come the spread of false information; myths that might influence how you deal with infections. But they’re exactly that: myths, and are highly likely untrue.

Here, we’ve debunked three of the most common myths about nail fungus:

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HOME REMEDIES EFFECTIVELY TREAT NAIL FUNGUS

Although some home remedies can treat mild cases of fungal infection, the risk of a recurring infection is relatively high. Home remedies also usually need a much longer time to take effect.

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FUNGAL INFECTIONS CAN BE TREATED WITH ANTIBIOTICS

While antibiotics are typically used to treat infections, it does not mean that they can easily treat fungal infections. It’s best to consult a doctor before taking any form of antibiotics, as taking them solely for fungal infections may cause adverse effects instead of treating the problem.

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FUNGAL INFECTIONS CAN GO AWAY ON THEIR OWN

This is by far one of the most common misconceptions about fungal infections. In fact, fungal infections can spread if left untreated. With all fungal infections, immediate attention is necessary. Make sure to get treatment as soon as you see the earliest signs of infection.

3 TRUTHS ABOUT NAIL FUNGUS TREATMENTS

Now that we’ve debunked the common misconceptions about nail fungus treatments, here is a checklist of three known facts to help you further understand how you can effectively and quickly get rid of this condition.

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NAIL FUNGUS IS RELATIVELY COMMON

This condition is surprisingly a lot more common than you think, and is much more likely to occur with age. Global Healing Center notes that about 5% of people suffer from nail fungus infection with toenail fungal infections being much more prevalent than fingernail.

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NAIL FUNGUS IS A TREATABLE CONDITION

You might have fallen into despair after the fifth home remedy failed, but the truth is, you can treat and successfully cure a nail fungal infection. Topical treatments, consistent care and preventive measures can eventually rid you of nail fungus entirely.

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YOU CAN PREVENT NAIL FUNGUS

Taking that extra bit of care with nail hygiene is the easiest way to prevent nail fungus. This includes regularly clipping and washing your toenails and fingernails. Other ways to prevent fungal infections include wearing slippers in public pools and showers, not sharing shoes, socks, or nail clippers, and only visiting nail salons that follow strict hygiene regulations.

After separating the facts from the fiction, it’s time to know which ingredients to look for – and which ones to avoid – in nail fungus treatments. Make sure you only take supplements that promise premium-quality formulation.

KEY INGREDIENTS IN HIGH-QUALITY NAIL FUNGUS TREATMENTS:

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NATURAL OILS

  • - Tea Tree Oil
  • - Sunflower Seed Oil
  • - Coconut Oil
  • - Lavender Oil

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DA-Approved Fungicide

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10% UNDECYLENIC ACID

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SD ALCOHOL 40D

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POLYSORBATE-20

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CETYL ALCOHOL

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GLYCERIN

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PHENOXYETHANOL

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ETHYLHEXYLGLYCERIN

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SNAKEROOT EXTRACT

UNWANTED NAIL FUNGUS TREATMENT INGREDIENTS

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ISOPROPYL ALCOHOL

Isopropyl alcohol does not fight yeast or other fungi. Additionally, applying this sterilizer may cause severe burning sensations on the infected tissue.

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HYDROGEN PEROXIDE AND HOUSEHOLD BLEACH

In low concentration treatments the fungi can still survive, but high concentrations of hydrogen peroxide can be toxic. Similar to bleach, it oxidizes the skin. Both are also highly flammable, and should be used with proper precautions.

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CICLOPIROX OLAMINE

Despite being known as an antifungal agent, there is lack of evidence that ciclopirox olamine is actually effective in treating fungal infections. This ingredient should be used with caution as some patients suffering from fungal infections may also have immune system conditions.

WHY AMAZON REVIEWS ARE NOT ALWAYS USEFUL

While research is important prior to purchasing certain products, you should be wary of where you gather information from. Many consumers turn to Amazon reviews – which might not be as reliable as you think. Up to 60% of those reviews are written by paid individuals, with some companies promising free products in exchange for a positive review.

OUR SPECIALIZED RANKING SYSTEM

This specialized ranking system follows a unique criteria and comprehensive process in which we measure the value of the products by carefully evaluating the ingredients, product safety, efficacy, refund policies, and overall customer satisfaction. These factors, combined with the latest studies and clinical trials, makes it easy to choose the best products available in the market, saving you both time and money.

2025 TOP 5 NAIL FUNGUS TREATMENTS IN THE MARKET

After extensive research, in consideration of combined ratings and online reviews from customers just like you, we’ve compiled a list of the top five nail fungus treatments on the market today.

1. EMONINAIL

by Emoninail

A+

Overall Grade

INGREDIENT SAFETY

PROJECTED EFFECTIVENESS
VALUE
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CUSTOMER SATISFACTION

INGREDIENT SAFETY

PROJECTED EFFECTIVENESS
VALUE
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CUSTOMER SATISFACTION
CUSTOMER SATISFACTION

INGREDIENT SAFETY

PROJECTED EFFECTIVENESS
VALUE
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CUSTOMER SATISFACTION

PROS

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Backed by clinical research

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Contains essential oils

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Easy brush application

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Supports healthy nail regrowth

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Helps clear yellow keratin

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Immediate results

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No side-effects

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60-day refund policy

CONS

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Individual results vary

THE BOTTOM LINE

Emoninail easily ranks as #1 on our top five list of nail fungus treatments. It contains undecyclenic acid as well as natural ingredients such as tea tree oil for both disinfection and nail penetration. It also helps clear yellow keratin for clearer nails. It’s an effective treatment that can show changes in as little as a couple of weeks. The product includes a brush for easy topical application. Emoninail has no known or reported side effects, but is backed by a 60-day refund policy. These factors make it both a safe and effective buying choice.

*Results are based on the nationalnailfungus.org website and do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.

2. FUNGINIX

by Funginix

A-

Overall Grade

INGREDIENT SAFETY

PROJECTED EFFECTIVENESS
VALUE
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CUSTOMER SATISFACTION

INGREDIENT SAFETY

PROJECTED EFFECTIVENESS
VALUE
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CUSTOMER SATISFACTION

INGREDIENT SAFETY

PROJECTED EFFECTIVENESS
VALUE
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CUSTOMER SATISFACTION

PROS

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Contains organic ingredients

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Strengthens nails

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Kills mild to moderate nail fungus

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Easy brush application

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90-day refund policy

CONS

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Results take a long time to show

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Strong odor

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May cause side-effects

THE BOTTOM LINE

Funginix makes it to #2 on our list of top five nail fungus treatments. The product uses organic ingredients to effectively strengthen nails, and kills mild to moderate nail fungi. However, Funginix may cause certain side-effects. Some users reported that it takes a long time to see any visible results despite months of regular use, while others said that their condition actually got worse upon using the product. The product is also said to have a strong, overwhelming smell. Fortunately, if you are unsatisfied with the product for any reason, Funginix is backed by a 90-day refund policy.

*Results are based on the nationalnailfungus.org website and do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.

3. ZETACLEAR

by Zetaclear

B+

Overall Grade

INGREDIENT SAFETY

PROJECTED EFFECTIVENESS
VALUE
RETURN POLICY

CUSTOMER SATISFACTION

INGREDIENT SAFETY

PROJECTED EFFECTIVENESS
VALUE
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CUSTOMER SATISFACTION

INGREDIENT SAFETY

PROJECTED EFFECTIVENESS
VALUE
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CUSTOMER SATISFACTION

PROS

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Contains 100% natural ingredients

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Clears yellow keratin

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Easy brush application

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90-day refund policy

CONS

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Results take a long time to show

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May cause mild burning sensation

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Refund policy is only for unopened bottles

THE BOTTOM LINE

Zetaclear ranks at #3 on our list of nail fungus treatments. It uses 100% natural ingredients, and clears yellow keratin to achieve healthier and clearer nails. The product comes with a brush for easy application. However, users stated that it takes quite a long time – give or take a few months – of regular use before they noticed any visible results. While it doesn’t have any side effects, the product may cause a mild burning sensation upon application. While they offer a 90-day refund policy, it only applies to unopened bottles.

*Results are based on the nationalnailfungus.org website and do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.

4. NATURASIL

by NATURASIL

B

Overall Grade

INGREDIENT SAFETY

PROJECTED EFFECTIVENESS
VALUE
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CUSTOMER SATISFACTION

INGREDIENT SAFETY

PROJECTED EFFECTIVENESS
VALUE
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CUSTOMER SATISFACTION

INGREDIENT SAFETY

PROJECTED EFFECTIVENESS
VALUE
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PROS

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Contains 100% plant extracts

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Relieves fungal infections

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Easily absorbed into skin and nails

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Easy brush application

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Bundle pack contains soap and supplements

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90-day refund policy

CONS

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Very few online reviews

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May take awhile to see visible results

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May cause burning sensation

THE BOTTOM LINE

Naturasil Nail Fungus Treatment ranks at #4 on our top five list of nail fungus treatments. It contains 100% plant extracts, and is free from harsh chemicals. It helps relieve fungal infections by easily absorbing into the skin and nails. It comes with a brush for easy topical application. However, some users reported that it takes a few months of regular use before they noticed any evident results, and others experienced a burning sensation after application.

There are also very few reviews of this product online, so it becomes pretty hard to measure its efficacy.

*Results are based on the nationalnailfungus.org website and do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.

5. NAIL RX

by NAIL RX

B-

Overall Grade

INGREDIENT SAFETY

PROJECTED EFFECTIVENESS
VALUE
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CUSTOMER SATISFACTION

INGREDIENT SAFETY

PROJECTED EFFECTIVENESS
VALUE
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CUSTOMER SATISFACTION

INGREDIENT SAFETY

PROJECTED EFFECTIVENESS
VALUE
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PROS

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100% natural ingredients

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No artificial preservatives

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Promotes healthy nail growth

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Addresses nail discoloration

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Supports healthy nail bed

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Can be bought in retail stores

CONS

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Very few online reviews

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No official website

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No refund policy

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Strong smell

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May cause side effects

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May cause stains

THE BOTTOM LINE

Nail-Rx ranks at #5 on our list of top five list of nail fungus treatments. It uses 100% natural ingredients with no artificial preservatives. It claims to promote healthy nail regrowth, fixes nail discoloration, and supports a healthy nail bed. The product doesn’t have an official website, and can, instead, be bought from retails stores. It does not, however, offer any refund policy. Some reviews mentioned that it has a strong smell, and can cause permanent stains on clothes, so it’s best to be careful about using this product. Because it has very few reviews online, there isn’t too much information about its efficacy.

*Results are based on the nationalnailfungus.org website and do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.

DISCLAIMER: nationalnailfungus.org is not responsible for the views or statements expressed by the writers. Any extraordinary results experienced by these individual are specified explicitly. Results vary with each individual user. Any progress made is not guaranteed and can vary depending on the said user. The information and opinions offered here on this website (nationalnailfungus.org) were written and designed for educational and entertainment purposes only. The information found here is not intended to substitute professional medical advice. It is not meant to treat, diagnose, or cure any medical condition. Please seek out medical advice from a licensed doctor or healthcare professional should you have any questions that are medical in nature. Parts of this website (nationalnailfungus.org) may—from time to time—contain information from visitors and other outside parties. nationalnailfungus.org is not responsible for any comments or information provided by the said visitors as well as others here on the website. nationalnailfungus.org reserves the right to review items posted in any part of the website and edit them for any reason at any given time. all the links in the table leads to external website.

AUTHORS

Dr. Jacob Moss M.D.

Dr. Moss M.D. is a General Practitioner in Colorado, earned MD and JD from Southern Illinois University Schools of Medicine and Law. He has published in 10 Peer Reviewed Medical journals

Pat-B

Pat B, Ph.D.

Pat holds a PhD in Natural Health and has been a Registered Nurse for 35 years. She earned certifications in American Herbalist's Guild, Registered Herbalist awarded in 2012. Pat has a license as Registered Nurse in New York awarded in 2011